UDK: 615.3:547.466.3:615.22

Anti-ischemic action of tolyl derivatives of gamma-oxybuteric acid

Perfilova V.N., Tyurenkov I.N.

Кафедра фармакологии и биофармации ФУВ, НИИ фармакологии ВолГМУ

Abstract

Tolibut is a new analog – malate, oxalate, succinate nicotinate, citrate, glutamate tolibut and complex tolibut with glycin – in doses 10–15 mg/kg improves functional states in myocardial ischemia, particularly during 30 minutes occlusion of coronary artery. Tolibut and its salts – malate and citrate have a more marked antiischemic effect.

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Contacts

Тюренков Иван Николаевич – д.м.н., профессор, зав. кафедрой фармакологии и биофармации ФУВ ВолГМУ, fibfuv@vistcom.ru