UDK: 616.8-091

PATHOMORPHOLOGY AND WATER-ELECTROLYTIC CONTENT IN PERITUMORAL BRAIN WHITE MATTER OF MALIGNANT NEUROECTODERMAL TUMORS

Yu. M. Zabrodskaya, O. N. Gaykova, O. A. Gan, A. V. Trophimova, K. V. Gadgiev

Российский научно-исследовательский нейрохирургический институт им. проф. А. Л. Поленова, Военно-медицинская академия им. С. М. Кирова*, Санкт-Петербургская медицинская академия им. И. И. Мечникова**, Санкт-Петербург

Abstract

We performed complex MRI-pathomorphological study of brains with histological examination of MRI hyperintense lesions. Materials included 11 cadaveric brains with malignant neuroectodermal tumors. We performed cell counting in peritumoral area. In 10 cases we investigated water content using method of drying, and electrolyte content by flame photometry. Peritumoral area has a complex reactive and destructive nature with elective (incomplete) brain tissue necrosis. Water accumulation is a secondary process with substitution of tissue elements by water. Authors propose to characterize peritumoral changes as peritumoral encephalopathy.

Keywords

brain, cancer, fluid and electrolyte composition.

Contacts

Забродская Юлия Михайловна — к. м. н., руководитель патологоанатомической лаборатории Российского НИИ нейрохирургии им. А. Л. Поленова, ст. преподаватель кафедры патологической анатомии Военно-медицинской академии им. С. М. Кирова, e-mail: zabrjulia@rambl