Journal of VolgSMU
Quarterly scientific-practical journal

UDK: 616.61-036.12-073.27-097.3

PECULIARITIES OF IMMUNOLOGICAL DISORDERS IN PERITONEAL DIALYSIS PATIENTS WITH VARYING DEGREES OF RISK OF DEVELOPMENT OF PERITONITIS

B. Yu. Gumilevskiy, O. P. Gumilevskaya, O. G. Kaburneeva

Кафедра иммунологии и аллергологии ВолгГМУ, Волгоградский областной уронефрологический центр

Abstract

This article presents data characterizing the peculiarities of immune status of patients with terminal stage renal disease receiving peritoneal dialysis, depending on susceptibility to dialysis peritonitis. It was shown that frequency of incidence and severity of the course of dialysis peritonitis depend on the extent of innate depression mechanisms and adaptive immunity, as well as imbalance of cytokine immunoregulation.

Keywords

dialysis peritonitis, terminal stage renal disease, cellular and humoral immunity.

Contacts

Гумилевский Борис Юрьевич — д. м. н., профессор, зав. кафедрой клинической лабораторной диагностики ВолгГМУ, e-mail: gumbu@mail.ru