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SEARCH FOR COMPOUNDS WITH ANALGETIC ACTIVITY AMONG 5-ARYL-4-AROYL- 3-ARYLAMINO-1-(2,2-DIMETHOXYETHYL)-3-PYRROL-2-ONES

E. B. Levandovskaya, V. N. Vichegjanina, V. L. Gein, B. Ya. Syropyatov

Пермская государственная фармацевтическая академия

Abstract

Interaction of 5-aryl-4-aroyl-3-hydroxy-1-(2,2-dimethoxyethyl)-3-pyrrol-2-ones with aromatic amines leads to formation of 3-arylaminoderivatives. The analgetic activity of compounds is investigated. The relationship between chemical structure of 5-aryl-4-aroyl-3-arylamino-1-(2,2-dimethoxyethyl)-3-pyrrol-2-ones and analgetic activity was studied.

Keywords

5-aryl-4-aroyl-3-arylamino-1-(2,2-dimethoxyethyl)-3-pyrrol-2-ones, aromatic amines, analgetic activity.

Contacts

Левандовская Елена Болеславовна — к. ф. н., докторант кафедры физической и коллоидной химии, e-mail: elenalevandovskaya@yandex.ru