UDK: УДК 340.67:615.212.7.099.074:543.544

DETERMINATION OF SOME OPIOID AND NON-OPIOID ANALGESIC DRUGS IN BIOLOGIC FLUIDS

A. A. Vatalev, A. V. Kireeva, N. A. Anisimova, V. N. Kuklin

Санкт-Петербургская государственная химико-фармацевтическая академия, Бюро судебно-медицинской экспертизы Ленинградской области*

Abstract

We have studied the conditions for isolation of analgesic drugs. We proposed a solvent for extraction, determined pH of the solution. We established the conditions for identification of analgesic drugs by using TLC, UV spectroscopy, chromatomass spectrometry, densitometry, and gas chromatography. We have shown that UV spectroscopy, HPLC and densitometry may be used for quantitative analysis. We have determined the stability of drugs in biological objects.

Keywords

analgesics, isolation, separation, identification.

Contacts

Ваталёв Андрей Александрович — аспирант кафедры фармацевтической химии СПХФА, e-mail:Vatalev_Andrew@mail.ru