UDK: УДК 616.24-002-085.281:616.379-008.64

FEATURES OF ALGORITHM FOR CHOICE OF ANTIBACTERIAL THERAPY OF COMMUNITY-ACQUIRED PNEUMONIA IN PATIENTS WITH DIABETES MELLITUS TYPE 2

N. V. Rogova, N. V. Shmidt, V. I. Statsenko, D. M. Serdukova, M. V. Gevorkyan

Кафедра клинической фармакологии и интенсивной терапии ВолгГМУ

Abstract

A prospective study of etiology of community-acquired pneumonia in 75 patients with diabetes mellitus type 2 in Volgograd was performed. Streptococcus pneumoniae (33,4 %), Klebsiella pneumoniae (13,4 %) and Staphylococcus aureus (13,4 %)were the most frequent isolates. Haemophilus influenzae, Mycoplasma pneumoniae, Chlamydophila pneumoniae, Enterobacter aerogenes were isolated from 8; 7; 9; 2,7 % and 1,3 % of all strains, respectively. Considering the database on the structure of bacterial pathogens and their local antimicrobial resistance, an algorithm for choosing antibiotics for the given group of patients is proposed. Amoxicillin/clavulanate, III— IV generation сephalosporins, carbapenems and their combination with macrolides or respiratory fluoroquinolones can be considered drugs for empiric therapy of non-severe community-acquired pneumonia; in severe pneumonia — with respiratory fluoroquinolones.

Keywords

community-acquired pneumonia, diabetes mellitus type 2, etiology, antibacterial therapy, local antimicrobial resistance.

Contacts

Шмидт Наталья Васильевна — соискатель кафедры клинической фармакологии и интенсивной терапии с курсами клинической фармакологии ФУВ, клинической аллергологии ФУВ ВолгГМУ, e-mail: natalyashmidt@mail.ru