UDK: 577.29.

INTENSITY OF FREE RADICAL PROCESSES AND SUPEROXIDE DISMUTASE ACTIVITY IN PATIENTS WITH DRUG-INDUCED HEPATITIS UPON COMBINED THERAPY WITH MELAXEN AND EPIFAMINE

S. S. Popov, K. K. Shulgin, A. N. Pashkov, V. I. Zoloedov, G. I. Shvedov

Воронежская государственная медицинская академия им. Н. Н. Бурденко, Воронежский государственный университет

Abstract

Inclusion of melaxen or epifamin into basic therapy of patients with drug-induced hepatitis was followed by correction of antioxidant status of the body, which was confirmed by a change in biochemiluminescence parameters and superoxide dismutase activity.

Keywords

drug-induced hepatitis, free radical processes, antioxidant system, superoxide dismutase, epifamin, melaxen.

Contacts

Попов Сергей Сергеевич — к. м. н., доцент кафедры эндокринологии, Воронежская государственная медицинская академия им. Н. Н. Бурденко, e-mail: popov-endo@mail.ru.