UDK: 618.33

THE ROLE OF DOPPLER DUCTUS VENOSUS BLOOD FLOW ASSESSMENT IN SCREENING FOR CHROMOSOMAL ABNORMALITIES IN THE FIRST TRIMESTER OF PREGNANCY

N. A. Altynnik

Институт повышения квалификации Федерального медико-биологического агентства РФ, Москва

Abstract

Doppler ductus venosus blood flow assessment was prospectively evaluated in 148 fetuses with Down syndrome at 11—14 weeks of gestation. The median maternal age was 32,15 years and 43,9 % of patients were 35 or older. Median gestation at screening was 12,2 weeks and the median fetal crown-rump length was 62,12 mm (45—84 mm). Abnormal ductus venosus blood flow waveforms were in 55,4 % (82/148) in fetuses with Down syndrome. The effectiveness of prenatal ultrasound screening for Down syndrome by combination of fetal nuchal translucency thickness and blood flow in ductus venosus at 11—14 weeks of gestation was 86,5 %.

Keywords

fetus, first-trimester screening, Doppler, chromosomal abnormalities, ductus venosus.

Contacts

Алтынник Наталья Анатольевна — к. м. н., доцент кафедры ультразвуковой и пренатальной диагностики ФГБОУ ДПО «Институт повышения квалификации ФМБА», е-mail: Natalia_altynnik@list.ru