UDK: 612.352.3:616.157 - 612.014.44

BCL-2 AND BAD PROTEINS EXPRESSION IN RAT LIVER AND CYTOKINES LEVEL IN BLOOD SERUM AT PERSISTING BACTERIAL INFECTION DURING ROUND-THE-CLOCK ILLUMINATION

I. P. Zhurakovsky, M. V. Bitkhaeva, S. A. Arkhipov, T. A. Kunts, M. G. Pustovetova, I. O. Marinkin

Новосибирский государственный медицинский университет

Abstract

It was revealed that expression of Bcl-2 protein family (Bcl-2, Bad) in Wistar rat liver depends on cytokines (IL-1, IL-1 RA, IL-2, IL-4, IL-6, IL-10, IL-17, IL-18, TNF-, INF-) level in blood serum at persisting bacterial infection caused by Staphylococcus aureus (strain 209) during round-the-clock illumination.

Keywords

bacterial infection, Staphylococcus aureus, apoptosis markers, Bcl-2, Bad, cytokines, round-the-clock illumination.

Contacts

Жураковский Игорь Павлович — к. м. н., ст. н. с., ГБОУ ВПО НГМУ Минздравсоцразвития РФ, e-mail: murash2003@yandex.ru