UDK: 796:616-008.615

STUDY OF VASODILATOR FUNCTION IN CONDITIONS OF EXTREME PHYSICAL AND PSYCHO-EMOTIONAL STRESS

A. V. Voronkov, N. A. Muravieva

Пятигорский медико-фармацевтический институт, филиал Волгоградского государственного медицинского университета, кафедра фармакологии, Пятигорск

Abstract

Endothelial dysfunction can be considered one of the key elements of the pathogenesis of pathological conditions associated with extreme physical overloads. NO-producing endothelial function is most vulnerable. The experiment revealed that intense physical loads lead to a decrease in efficiency in animals, deterioration of endothelial vasodilator function of endothelium in the modification of the synthesis and release of endogenous nitric oxide.

Keywords

physical load, psycho-emotional overload, endothelial dysfunction, sympathoadrenal system, oxidative stress, metabolic disorders.

Contacts

Воронков Андрей Владиславович — д. м. н, зав. кафедрой фармакологии и патологии Пятигорского медико-фармацевтического института — филиала Волгоградского государственного медицинского университета, Пятигорск, e-mail: prohor.77@mail.ru