UDK: 615.451.1.015.14:616.61-092.9

STUDY OF NEPHROPROTECTIVE ACTION OF DRY EXTRACT FROM ROOTS OF SCUTELLARIA BAICALENSIS AND ITS COMPLEX OF INCLUSION WITH 2- HYDROXYPROPYL--CYCLODEXTRIN UPON MERCURY (II) CHLORIDE INTOXICATION

E. G. Dorkina, A. A. Potapova, E. O. Sergeeva, L. A. Sadzhaya, L. I. Scherbakova

Пятигорский медико-фармацевтический институт

Abstract

The dry extract from Scutellaria baicalensis at a dose of 300 mg/kg body weight and its complex of inclusion with 2-hydroxypropyl--cyclodextrin at a dose of 15 mg/kg weight have an equivalent and more marked nephroprotective action compared with the standard medicine «Urokam» in toxic damage of kidney by mercury (II) chloride in rats.

Keywords

Scutellaria baicalensis, dry extract, inclusion complex with 2-hydroxypropyl--cyclodextrin, mercury (II) chloride intoxication, nephroprotection.

Contacts

Доркина Елена Григорьевна — д. б. н., доцент, заведующая кафедрой биохимии и микробиологии, ПМФИ — филиал ГБОУ ВПО ВолгГМУ МЗ РФ, e-mail: elenadorkina@yandex.ru