UDK: 615.214.31:616.89-008.46-092.4

EFFECTS OF PHENIBUT ON MEMORY AND BEHAVIOR IN RATS OF DIFFERENT AGE SUBJECTED TO 7-DAY COMBINED EMOTIONAL STRESS

E. V. Volotova, D. V. Kurkin, D. A. Bakulin, I. S. Filina, I. N. Tyurenkov

Волгоградский государственный медицинский университет, кафедра фармакологии и биофармации ФУВ

Abstract

Influence of phenibut on neuropsychiatric status of rats of varying age after a long combined stress exposure was studied. Impairment of mental functions was established in older animals (24 months). 7-day administration of phenibut (25 mg/kg) before each stress exposure contributes to maintenance of memory status of rats.

Keywords

stress, age, memory, phenibut, rats.

Contacts

Волотова Елена Владимировна — к. м. н., ассистент кафедры фармакологии и биофармации ФУВ, Волгоградский государственный медицинский университет, e-mail: evv.md@yandex.ru