UDK: 616.61-005.6:575

CYTOKINE PATTERN FEATURES OF PATIENTS WITH RECURRENT THROMBOSIS OF ARTERIOVENOUS FISTULA RECEIVING HEMODIALYSIS

O. P. Gumilevskaya, K. P. Vakhaniya, N. S. Rakitina

Волгоградский государственный медицинский университет, кафедра клинической лабораторной диагностики

Abstract

Serum levels (IL-1, IL-4, IL-6, IL-10, IFN-, TNF-) and polymorphism of the promoter region of cytokine genes (IL-6, IL-10, IL-1, TNF-) from 104 patients receiving hemodialysis were studied. It was revealed that the development of thrombotic complications of arteriovenous fistula is associated with structural features of cytokine genes IL-10 and IL-4, as well as serum levels of IL-6, IL-10, TNF-, IFN-.

Keywords

cytokines, allelic polymorphism, dialysis, chronic kidney disease.

Contacts

Гумилевская Оксана Петровна — профессор кафедры клинической лабораторной диагностики с курсом КЛД ФУВ, Волгоградский государственный медицинский университет, e-mail: ogum@mail.ru.