UDK: 615.1:542.74

CHROMATOGRAPHY OF A NEW ADENINE DERIVATIVE WITH ANTIVIRAL ACTIVITY

L. A. Smirnova, E. A. Suchkov, A. F. Riabuha, K. A. Kuznetsov, A. A. Ozerov

Научно-исследовательский институт фармакологии, Волгоградский государственный медицинский университет, кафедра фармацевтической и токсикологической химии

Abstract

An optimal chromatographic condition of HPLC method of quantitative determination of the adenine derivative VMA-99-82 was developed. This is a highly sensitive and highly selective method and can be quite helpful in bioassays. The method of sample preparation has been adjusted optimally; it does not have any effect on the standard error of quantitative determination.

Keywords

HPLC, adenine derivatives, quantitative determination.

Contacts

Сучков Евгений Александрович — м. н. с. лаборатории фармакологической кинетики НИИ фармакологии, ВолгГМУ, e-mail: ewgenik@gmail.com