UDK: 579.61

CYTOTOXIC EFFECT OF BURKHOLDERIA CEPACIA ON TETRAHYMENA PYRIFORMIS CELLS IN COMMON CULTURE

E. V. Korol, L. K. Merinova, M. O. Nekhezina, E. V. Shubnikova

Волгоградский научно-исследовательский противочумный институт

Abstract

The conducted research showed that the microorganisms of B. cepacia complex are resistant to the phagositic activity of T. pyriformis. The cytotoxic effect of B. cepacia against Tetrahymena cells is manifested in the fact of protozoan incystment. The intensity of this process depends on bacterial strain. Thus the most pronounced incystment was observed upon interaction with the strain of B. cepacia 323, a clinical isolate showing enhanced virulence for experimental animals.

Keywords

Burkholderia cepacia, Tetrahymena pyriformis.

Contacts

Король Екатерина Васильевна — научный сотрудник лаборатории генетики, ФКУЗ Волгоградский научно-исследовательский противочумный институт Роспотребнадзора, Волгоград, Россия, e-mail: vari2@sprint-v.com.ru