UDK: 618.3-008.6-085.31-092.4

CORRECTION OF ABNORMALITIES IN POSTNATAL DEVELOPMENT OF RAT OFFSPRING WITH EXPERIMENTAL PREECLAMPSIA BY NEW GABA COMPOUND RGPU-242 DERIVATIVES

L. I. Mikhailova, G. A. Zhakupova

Волгоградский государственный медицинский университет, кафедра фармакологии и биофармации ФУВ

Abstract

The article presents the results of a study of postnatal development of rat offspring with experimental preeclampsia induced by replacing drinking water by 1,8% sodium chloride solution from the 7th to the 21st day of gestation. Beneficial effect of compound RGPU-242, a new GABA derivative, on the physical development and maturation rate of sensory-motor reflexes in the offspring.

Keywords

experimental preeclampsia, physical development of the offspring, sensory-motor reflexes, GABA derivative.

Contacts

Михайлова Людмила Ивановна — аспирант кафедры фармакологии и биофармации ФУВ, ВолгГМУ, e-mail: mih-li@mail.ru