UDK: 615:616.379-008.64

PHARMACOEPIDEMIOLOGICAL ANALYSIS OF ANTIBIOTIC THERAPY IN PATIENTS WITH URINARY TRACT INFECTIONS AND DIABETES MELLITUS TYPE 2

O. I. Butranova, N. G. Syrodoeva

Abstract

The retrospective pharmacoepidemiological study of 280 medical records (patients with urinary tract infections and diabetes mellitus type 2) revealed that the predominant infection was chronic pyelonephritis (82,4 %); most typical microbial agents were E. coli (40 %), Kl. pneumoniae (20 %), Ent. faecalis (18 %) with marked levels of resistance to cephalosporines, aminopenicillines,fluorchinolones; the effective antibiotics were amoxicilline/clavulanate, vancomycine, 2nd and 3rd generation fluorchinolones.

Keywords

diabetes mellitus type 2, urinary tract infections, antibiotic therapy, bacterial sensitivity, bacterial resistance, pharmacoepidemiological study.

Contacts

Сыродоева Надежда Геннадьевна — клинический ординатор кафедры клинической фармакологии и интенсивной терапии с курсами клинической фармакологии ФУВ, клинической аллергологии ФУВ, ВолгГМУ, e-mail: Nadezhda_GS@bk.ru