UDK: 616.314.17-008.1-097:616.4
I. V. Starikova, N. V. Piterskaya, N. N. Trigolos, T. N. Radyshevskaya, N. F. Aleshina, E. M. Chaplieva
Волгоградский государственный медицинский университет, кафедра терапевтической стоматологии
We studied the changes in local immune reactions in gingival fluid samples obtained from 40 patients aged 35—55 years with chronic generalized periodontitis (CGP) and metabolic syndrome (MS) to add membrane plasmapheresis (PA)to standard care. The patients were divided into two groups. The first group received standard treatment. The second group received membrane plasmapheresis in addition to standard therapy. The analysis of the local immunogram obtained from patients with chronic generalized periodontitis of moderate severity accompanied by metabolic syndrome showed significant changes in nonspecific immunity. After completing the standard treatment, the immune parameters of the patients in the first group failed to reach the same levels as in the control group, which was accounted for by compromised immunity and especially its local component. Long-term results show that patients in the first group are more likely to develop acute inflammation in the periodontal tissues. In the group of patients where membrane plasmapheresis was used, cellular immunity did not significantly differ from that in the control group.
periodontal disease, metabolic syndrome, local oral immunity.
Радышевская Татьяна Николаевна — к. м. н., ассистент кафедры терапевтической стоматологии, Волгоградский государственный медицинский университет, e-mail: Radyshevska@mail.ru