UDK: 616.36-006.3

NONALCOHOLIC FATTY LIVER DISEASE AS A MULTISYSTEM DISEASE

Волгоградский государственный медицинский университет, кафедра внутренних болезней педиатрического и стоматологического факультетов

Abstract

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease. Over the last decade, it has been shown that the clinical burden of NAFLD is not only confined to liver-related morbidity and mortality, but there is now growing evidence that NAFLD is a multisystem disease, affecting extra-hepatic organs. For example, NAFLD increases risk of type 2 diabetes mellitus (T2DM), cardiovascular (CVD) and cardiac diseases, and chronic kidney disease (CKD). The review discusses the factors involved in the progression of liver disease in NAFLD and the factors linking NAFLD with other extrahepatic chronic diseases, such as CVD and CKD.

Keywords

non-alcoholic fatty liver disease; сardiovascular disease; сhronic kidney disease.

Contacts

Стаценко Михаил Евгеньевич — д. м. н., профессор, зав. кафедрой внутренних болезней педиатрического и стоматологического факультетов, Волгоградский государственный медицинский университет, e-mail: mestatsenko@rambler.ru