UDK: 615.212.7:616-092.9

ANALGETIC ACTIVITY OF A BENZIMIDAZOLE DERIVATIVE ON MODELS OF INFLAMMATORY PAIN

O. Yu. Grechko, N. V. Eliseeva, A. A. Spasov, R. A. Litvinov

1Волгоградский государственный медицинский университет, кафедра фармакологии

Abstract

We studied the analgesic activity of RU-1205, a benzimidazole derivative, on the models of inflammatory pain.The derivative has been found to exhibit pronounced analgesic activity in both acute and chronic experimental pain models.

Keywords

kappa-opioid receptor, opioid analgesics, inflammatory pain, formalin, butorphanol.

Contacts

Елисеева Наталья Владимировна — к. м. н., ассистент кафедры фармакологии, Волгоградский государственный медицинский университет, e-mail: nvkirillova@rambler.ru