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ASSESSMENT OF ORAL MICROCIRCULATION DURING THE TREATMENT OF INFLAMMATORY AND DESTRUCTIVE DISEASES OF THE ORAL MUCOSA USING PLATELET-DERIVED AUTOPLASMA

Yu. A. Makedonova, S. V. Poroyskiy1, I. V. Firsova

Волгоградский государственный медицинский университет, кафедра терапевтической стоматологии, 1Волгоградский медицинский научный центр, лаборатория моделирования патологии

Abstract

Although a lot of methods for diagnosing and treating diseases of the oral mucosa are currently available, one of the most challenging aspects of dentistry is the choice of the most appropriate treatment. There has been a growing interest in the use of laser Doppler flowmetry as a diagnostic means of oral microcirculation disorders. The mainstay of the therapy of inflammatory diseases of the oral mucosa is a local treatment. The other aspect of treatment involves elimination of the causative agents of the disease. In this relation noninvasive methods hold great potential for the treatment of inflammatory diseases of the oral mucosa. We compared microcirculation before treatment and after 14 days of treatment in patients with lichen planus. All the patients were divided into two groups based on the type of treatment that they received. The first group received conventional therapy; the second group received conventional therapy plus platelet-derived autoplasma. Data analysis showed that laser Doppler flowmetry is useful in evaluating microcirculatory changes in patients with oral erosive and ulcerative lesions. Combination of laser Doppler flowmetry and clinical investigations contribute to a better understanding of how much tissue is affected. Autohemotherapy was shown to improve the oral microcirculation in the short-term.

Keywords

microcirculation, autohemotherapy, lichen planus, erosion, ulcer. Распространенность заболеваний слизистой обо- лочки полости рта увеличивается с каждым годом [9]. При данной патологии, по данным различных авторов, снижение качества жизни пациента является самой час- той проблемой у пациентов всех возрастных групп [2]. Актуальной является проблема ранней диагностики и лечения воспалительно-деструктивных заболеваний слизистой полости рта [7]. При лечении заболеваний слизистой безусловный приоритет принадлежит в при- менении местных противовоспалительных медикамен- тозных средств, без

Contacts

Македонова Юлия Алексеевна — к. м. н., ассистент кафедры терапевтической стоматологии, Волгоградский государственный медицинский университет, e-mail: mihai-m@yandex.ru