Journal of VolgSMU
Quarterly scientific-practical journal

UDK: 577.29:615

EFFECT OF EXPERIMENTAL CHRONIC ALCOHOL INTOXICATION ON ENDOGENOUS INTESTINAL MICROFLORA

L. P. Knyshova1, 2, 3, S. V. Poroysky1, 2, A. T. Yakovlev4, E. I. Morkovin3, 4

1Волгоградский государственный медицинский университет, кафедра медицины катастроф, 2ГБУ ВМНЦ, лаборатория моделирования патологии, 3ГБУ ВМНЦ, лаборатория геномных и протеомных исследований, 4НИИ фармакологии, лаборатория психофармакологии, 5Волгоградский

Abstract

The problem of alcohol abuse of children and adolescents, related reduction of labor potential, social tensions can be seen as the major threat to national security. In the present study evaluated the changes of intestinal microflora in experimental chronic endogenous alcohol intoxication in rats as a constituent of the concept of resistance of the organism. The findings are part of a clinical and experimental study of the resistance state changes of an organism subjected to acute and chronic effects of alcohol.

Keywords

alcoholism, endogenous intoxication, microbiocenosis intestine, experimental modeling.

Contacts

Кнышова Лилия Петровна — преподаватель кафедры медицины катастроф, Волгоградский государственный медицинский университет, e-mail: knyshovaliliya@ inbox.ru