UDK: [615.214.22.099:616-008.843.1].074

ISOLATION, DETECTION AND QUANTIFICATION OF ALIMEMAZINЕ IN MODEL MIXTURES OF URINE, SALIVE AND BLOOD PLASMA

Пятигорский медико-фармацевтический институт — филиал ФГБОУ ВО ВолгГМУ Минздрава России, г. Пятигорск

Abstract

The article presents the study of the techniques of detecting and quantifying mixtures in models of alimemazine urine, saliva and blood plasma. To isolate alimemazine from biological fluids a method of liquid-liquid extraction analyzing the physicochemical properties of the analyte has been suggested. The detection was carried out using TLC and HPLC quantification — HPLC.

Keywords

alimemazine, model mix.

Contacts

Рыбасова Анна Сергеевна — аспирант кафедры фармацевтической и токсикологической химии, Пятигорский медико-фармацевтический институт — филиал ФГБОУ ВО ВолгГМУ Минздрава России, e-mail: anna.rybasova@yandex.ru