UDK: 6.16.728.3-002-001-08

METALLOPROTEINASES 1 AND 13 AS MARKERS OF DESTRUCTIVE AND PROLIFERATIVE PROCESSES IN THE ARTICULAR CARTILAGE IN EXPERIMENTAL OSTEOARTHRITIS

S. A. Demkin 1, D. A. Malanin1, L. N. Rogova1, G. L. Snigur1, N. V. Grigorieva1, K. V. Baydova2

1Волгоградский государственный медицинский университет, 2Волгоградский медицинский научный центр

Abstract

The present study investigated the dynamics of the activity of MMP-1 and MMP-13 hyaline cartilage in rats with experimental osteoarthritis of the knee which was followed by a comparative analysis of the data with morphometric parameters.

Keywords

osteoarthritis, hyaline cartilage, metalloproteinase.

Contacts

Дёмкин Сергей Анатольевич — врач травматолог-ортопед, Госпиталь ФКУЗ МСЧ МВД России по Волгоградской области, e-mail: smdem@mail.ru