UDK: 618.15-002:615.8
O. I. Marushkina, N. A. Zharkin, N. Wang
Волгоградский государственный медицинский университет, кафедра акушерства и гинекологии
The efficacy of probiotics, containing lactobacillus сaseir hamnosus spp., and balneotherapy in comprehensive treatment of bacterial vaginosis (BV) was evaluated. 107 patients were examined. 51 patients were given probiotics and 56 patients were treated with balneological factors (mud and brine) after receiving Imidazole antimicrobial therapy. Complaints, data of objective examination, pH-metry, smear microscopy, bacteriological investigation and a semiquantitative method of a real-time polymerase chain reaction were analyzed to evaluate the efficiency of treatment. After balneological treatment at its second stage, a considerable increase in lactobacillus pool was revealed in a long-term perspective. It was 2.5 times higher than that after probiotics (p < 0,01) were used in conventional treatments to restore the vaginal tract.
bacterial vaginosis, comprehensive treatment, probiotics, microbial biofilms, balneotherapy.
Ван Нянь — аспирант кафедры акушерства и гинекологии, Волгоградский государственный медицинский университет, email: Wangnan821025@gmail.com