Journal of VolgSMU
Quarterly scientific-practical journal

UDK: 54.061:543.89:543.42.062

DEVELOPMENT AND VALIDATION OF THE SPECTROPHOTOMETRIC TECHNIQUE FOR QUANTITATIVE ANALYSIS OF A NEW BIOLOGICALLY ACTIVE COMPOUND, A DERIVATIVE OF-4 (3H)-ONE QUINAZOLINE

D. S. Volokitina, A. A. Ozerov, D. S. Lazaryan, S. V. Volokitin

1Волгоградский государственный медицинский университет, кафедра фармацевтической и токсикологической химии, 2Пятигорский медико-фармацевтический институт — филиал ФГБОУ ВО ВолгГМУ Минздрава России, кафедра фармацевтической и токсикологической химии

Abstract

In this study, we investigated the possibility of using UV spectrophotometry to quantify of a new substance, a bioactive compound derived from -4(3H)-one quinazolin. A new analytical technique was developed and validated. The technique meets the requirements for the analytical procedures for pharmaceutical substances.

Keywords

quinazoline derivative, quantification, spectrophotometry, validation, eligibility criteria.

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