UDK: 616-002

Role of dynamic eustress in development of systemic inflammatory process: experimental and clinical study

A.G. Kurygin

Ярославская государственная медицинская академия

Abstract

The role of dynamic eustress in development of adjuvant arthritis and rheumatoid arthritis has been studied. 30 laboratory male rats were studied. Parameters of dynamics of adjuvant arthritis, products of lipid metabolism and lipid peroxidation were registered. 45 patients with rheumatoid arthritis were surveyed. Development of adjuvant disease was accompanied by essential changes in dynamics of investigated parameters, including products of lipid peroxidation. Daily dynamic eustress decreased the development of systemic inflammation almost in all investigated parameters; it also decreased the level of products of lipid peroxidation. Positive stress in clinical setting (graduated exercise) also had a positive therapeutic effect.

Keywords

adjuvant arthritis, rheumatoid arthritis, eustress

Contacts

Курыгин Александр Георгиевич – к.м.н., ассистент кафедры терапии педиатрического факультета Ярославской государственной медицинской академии, E-mail: ag-k@nm.ru