Journal of VolgSMU
Quarterly scientific-practical journal

UDK: 616.44-036.12:572.7

Morphogenesis of “small nodules” in thyroid gland

A.A. Filin, V.I. Danilenko

Воронежская государственная медицинская академия им. Н.Н. Бурденко

Abstract

Asymptomatic pathology of thyroid gland in 54 postmortems (age 59,5±12,3) was investigated. "Small" locuses (0,35±0,2см) of non-cancerous tissue growth (181 "nodules") were found in 39 cases (72,2 %). About a half of "nodules" (78 of 181) had elements of radial symmetry. It was established that a structural unit of non-cancerous growth in the thyroid is "proliferation centers" ("symmetric nodules"). Nodular hyperplasia in the thyroid begins with pictures of proliferation. Structures like "adenomas", cysts arise later. At later stages of the process there comes atrophy and sclerosis of hyperplastic locuses.

Keywords

thyroid gland, nodular hyperplasia, cancer, morphogenesis

Contacts

Виталий Иванович Даниленко – д.м.н., профессор, зав.кафедрой патологической анатомии Воронежской государственной медицинской академии им.Н.Н.Бурденко, E-mail: vitad@rambler.ru