UDK: 614.2:616-01

VALIDATION AND PSYCHOMETRIC EVALUATION OF A QUESTIONNAIRE TO STUDY DISEASE ACTIVITY IN SYSTEMIC LUPUS ERYTHEMATOSUS

E.A. Sushchuk, I.Y. Kolesnikova, S.I. Krajushkin

ФГБОУ ВО «Волгоградский государственный медицинский университет» Министерства здравоохранения Российской Федерации, кафедра амбулаторной и скорой медицинской помощи

Abstract

Further validation and estimation of psychometric properties of a questionnaire for self-assessment of disease activity in systemic lupus erythematosus (SLE) patients was performed. Investigation included 129 SLE patients with various degrees of disease activity and variable clinical features. Factor and cluster analyses reviled internal structure of the questionnaire which reflects SLE activity in musculoskeletal system, internal organs, constitutional features, nervous system and integuments. Rasch-analysis confirmed unidimentionality and internal validity of the questionnaire with acceptable discriminatory and items reliability parameters. External validity was proven by positive correlation with SLE activity measures by accepted indices. It was detected that patient’s perception of SLE activity is determined not only by obvious clinical manifestations of the disease but also by some laboratory parameters.

Keywords

systemic lupus erythematosus, disease activity, activity index, questionnaire, validity, Rasch-analysis.

Contacts

Сущук Евгений Александрович – к. м. н., доцент кафедры амбулаторной и скорой медицинской помощи, Волгоградский государственный медицинский университет, e-mail: eugene.sushchuk@gmail.com