UDK: 617.723

CHANGES IN HORMONAL REGULATION IN PATIENTS WITH ACUTE AND CHRONIC FORMS OF CENTRAL SEROUS CHORIORETINOPATHY

A.A. Schuko1, L.F. Sholokhov3, A.N. Zlobina1, T.N. Iureva1,2

1Иркутский филиал ФГАУ НМИЦ МНТК «Микрохирургия глаза им. акад. С.Н. Федорова» Министерства здравоохранения Российской Федерации; 2Иркутская государственная медицинская академия последипломного образования – филиал ФГБОУ ДПО «Российская медицинская академ

Abstract

A study of the concentration of stress hormones was conducted in 16 patients with acute and in 18 patients with the chronic form of central serous chorioretinopathy. In patients with central serous chorioretinopathy, there is an increase in blood concentrations of cortisol and 17-OH-oxyprogesterone, a 25–32 % reduction in the concentration of thyroid stimulating hormone with a constant content of thyroxin was detected, а decrease in testosterone concentration and the concentration of melatonin in the urine was significantly reduced. Thus, the obtained data prove the validity of the idea of a close connection and interdependence of the revealed changes in the hormonal regulation in the pathogenesis of central serous chorioretinopathy.

Keywords

hormonal regulation, acute and chronic form of central serous chorioretinopathy.

Contacts

Щуко Алексей Андреевич – к. м. н., медицинский психолог ИФ ФГАУ «НМИЦ «МНТК «Микрохирургия глаза» им. акад. С.Н. Федорова Минздрава России, e-mail shukoa11@mail.ru