UDK: 616.12-008.331.1-085+615.252.349.7

INFLUENCE OF COMBINATION THERAPY ON THE FUNCTIONAL CONDITION OF VASCULAR ENDOTHELIAL IN PATIENTS WITH ARTERIAL HYPERTENSION WITH SITUATION DEPRESSION LIVING ON DONBASS

O.S. Nalyotova

ГОО ВПО «Донецкий национальный медицинский университет им. М. Горького»

Abstract

The article presents the results of the effect on the vasodilating function of the endothelium of complex treatment of patients with arterial hypertension stage II with identified situational depression living in Donbas. Additional inclusion in the standard antihypertensive pharmacotherapy of the psychotherapeutic complex auto-training + functional music + L-arginine (0,75 once a day) has been shown to effectively eliminate vascular endothelial dysfunction, which was manifested by a change in the diameter of the brachial artery (p < 0,001) in response to an increase in speed blood flow (p < 0,05) after external occlusion in this group of patients after 24 weeks of treatment is similar to the change in healthy volunteers (p < 0,05).

Keywords

arterial hypertension, situational depression, auto-training, functional music, L-arginine.

Contacts

Налётова Ольга Сергеевна – к. м. н., ассистент кафедры фармакологии и клинической фармакологии имени профессора И.В. Комиссарова ГОО ВПО «Донецкий национальный медицинский университет им. М. Горького», г. Донецк, ДНР, e-mail: sergiy.nalotov@gmail.com