UDK: 616. 31:616.516-085.31

EFFICIENCY OF TOPICAL APPLICATION OF MUCOADHESIVE DRUGS FOR TREATING RED FLAT LICHEN OF THE ORAL CAVITY

I.V. Firsova1, Yu.M. Fedotova1, S.V. Porojskij2, Yu.A. Makedonova1, 2, V.F. Mihalchenko1

1ФГБОУ ВО «Волгоградский государственный медицинский университет» Министерства здравоохранения Российской Федерации, кафедра терапевтической стоматологии; 2ГБУ «Волгоградский медицинский научный центр», лаборатория моделирования патологии

Abstract

In the comparative aspect, the clinical efficacy of modern topical mucoadhesive drugs belonging to different types of transport systems of local drug delivery was studied. The study included 90 patients with erosive form of red flat lichen of the oral cavity, in the local treatment of which traditional forms (ointment) of drugs and drugs with high mucoadhesive properties (gel and polymer film) were used. The results of the study demonstrate the most active nature of epithelialization and regression of inflammation of oral mucosa in patients using mucoadhesive drugs, and justifies their use as a local therapeutic system.

Keywords

lichen planus, mucoadhesive funds, local drug delivery, erosion, oral cavity.

Contacts

Фирсова Ирина Валерьевна – д. м. н., профессор, зав. кафедрой терапевтической стоматологии, Волгоградский государственный медицинский университет, e-mail: ivfirsova@volgmed.ru