Journal of VolgSMU
Quarterly scientific-practical journal

UDK: 616.314-089.27

CYTOLOGICAL METHOD OF RESEARCH IN THE DIAGNOSIS AND TREATMENT OF LICHEN PLANUS OF THE ORAL MUCOSA

S.B. Poroisky1, 3, I.V. Firsova2, Yu.A. Makedonova2, A.V. Poroiskaya4, Yu.M. Fedotova2

ФГБОУ ВО «Волгоградский государственный медицинский университет» Министерства здравоохранения Российской Федерации, 1Лаборатория моделирования патологии; 2Кафедра терапевтической стоматологии; 3Кафедра медицины катастроф; 4Кафедра патологической анатомии

Abstract

One of the common inflammatory and destructive diseases in gerontostomatology is lichen planus. The course of this pathology is long, persistent and chronic. Early methods of diagnosing the disease, timely pharmacotherapy are the key to success in the treatment of lichen planus. Cytological method of research refers to the methods by which you can quickly get the results and adjust the scheme of drug symptomatic treatment of erosive and ulcerative lesions in the oral cavity. It is based on the study of the structural features of cellular elements. In this work, we examined and treated 60 patients with erosive-ulcerative form. In 30 people, in addition to traditional treatment, Titol's applications with a 0,1 % betamethasone solution are included in the scheme of complex therapy; in the second half of the patients, applications of betamethasone, fixed using a mucoadhesive polymer film, are used. In the resulting scrapings under magnification of x400 and x1000, the evaluation of the stage of destruction of epithelial cells with the corresponding morphological characteristic was made. In both cases, a positive trend was noted, however, the cytological picture was different depending on the type of drug therapy.

Keywords

lichen planus, cytology, betamethasone, Tizol.

Contacts

Поройский Сергей Викторович – д. м. н., заведующий кафедрой медицины катастроф, Волгоградский государственный медицинский университет, e-mail: poroyskiy@mail.ru