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LEFT HEART CHAMBERS REMODELING IN PATIENTS WITH RHEUMATOID ARTHRITIS WITH METABOLIC SYNDROME

Yu.I. Lisitsina1, L.N. Shilova1, A.V. Alexsandrov1, 2

1ФГБОУ ВО «Волгоградский государственный медицинский университет» Министерства здравоохранения Российской Федерации, кафедра госпитальной терапии, ВПТ с курсом клинической ревматологии ФУВ; 2ФГБНУ «Научно-исследовательский институт клинической и экспериме

Abstract

The study included 87 patients with a reliable diagnosis of rheumatoid arthritis (RA), who were divided into two groups based on the presence of criteria for metabolic syndrome (MS). The parameters of lipid profile, morphometric, functional parameters of the left heart, signs of atherosclerosis of the aorta by Echocardiography were studied. MS components were found in 53 people (60,9 %). The thickness of the interventricular septum, the posterior wall of the left ventricle (LV), LV myocardial mass index, indices of the time of early diastolic filling blood flow slowdown, LV isovolumetric relaxation time in patients with RA and RA and MS combination were higher than in the control group. Average values of end-systolic, end-diastolic sizes, LV ejection fractions were within normal limits. Almost all patients with MS showed signs of atherosclerosis of the aorta, a higher rate of atherogenicity, a tendency to form a concentric type of remodeling of the left heart, as well as diastolic dysfunction by hypertrophic type.

Keywords

rheumatoid arthritis, metabolic syndrome, left ventricular remodeling, diastolic dysfunction.

Contacts

Лисицина Юлия Ильинична – аспирант кафедры госпитальной терапии, ВПТ с курсом клинической ревматологии ФУВ, ВолгГМУ, e-mail: edelveis_888@mail.ru