UDK: 616.37-002-092.4:546.46

MAGNESIUM BALANCE IN THE BODY IN EXPERIMENTAL PANCREATITIS IN RATS WITH NORMAL AND LOW LEVELS OF MAGNESIUM CONTENT IN ERYTROCYTE MASS

L.N. Rogova, N.V. Grigor eva, T.I. Shepeleva, M.V. Ermak, V.S. Egorova

ФГБОУ ВО «Волгоградский государственный медицинский университет» Министерства здравоохранения Российской Федерации, кафедра патофизиологии, клинической патофизиологии, кафедра патологической анатомии

Abstract

Pancreatitis was modeled in rats with the initial normal and low concentration of magnesium in the erythrocyte mass. Morphological signs of pancreatitis were revealed in the tissues obtained seven days after the modeling. Slight decrease of magnesium content in erythrocyte mass from subclavian and portal collectors and vena cava inferior and increase of its losses with urine was determined in experimental animals with the normal level of magnesium against the background of the pancreatitis. Increasing concentration of magnesium in plasma and erythrocyte mass of blood from different collectors, as well as increasing its losses in the urine in rats with a low initial intracellular magnesium content.

Keywords

normal and low intracellular magnesium concentration, experimental pancreatitis, plasma magnesium, magnesium in erythrocyte mass.

Contacts

Рогова Людмила Николаевна – д. м. н., профессор, зав. кафедрой патологической физиологии и клинической патофизиологии, Волгоградский государственный медицинский университет, e-mail: rogova.ln@mail.ru