UDK: 616.33/34-008.1-07

CLINICAL SIGNIFICANCE OF EVALUATION OF NEUROMEDIATERS AND CYTOKINES IN PATIENTS WITH FUNCTIONAL GASTROINTESTINAL DISORDERS

Кафедра факультетской терапии ВолГМУ

Abstract

Examination of the 67 patients with the functional gastrointestinal disorders (FGID) by means of ELISA test demonstrated a decrease in endogenous serotonin and melatonin level with the simultaneous elevation of inflammat ory cytokine concentration. Revealed neuroendocrine and cytokine changes suggest contribution of neurohumoral and cytokine systems in development of FGID.

Keywords

functional dyspepsia, irritable bowel syndrome, serotonin, melatonin, interleukines, cytokines.

Contacts

Бабаева Аида Руфатовна – д.м.н., профессор, зав.кафедрой факультетской терапии ВолГМУ, babaeva_ar@volgmed.ru