UDK: 616-091:618.11:616.8

MORPHOLOGICAL CHARACTERISTICS OF THE OVARIES IN CHEMO-INDUCED STRESS

A. G. Denisov, A. V. Smirnov

Отдел общей и экспериментальной патологии ГУ ВНЦ РАМН и Администрации Волгоградской области

Abstract

In the paper structural changes in the rats’ ovaries under chemo-induced stress were characterized. Atrophic changes in the ovaries of the experimental animals, increased incidence of apoptotic cells in them, especially in the yellow bodies, decreased size of the corpora lutea and granulous luteocytes in them observed against the background of decreased concentration of estradiol, progesterone, prolactine and luteinizing hormone, yield eviden ce of development of hormonal disbalance at different levels of ovarian functions regulation.

Keywords

ovary, chemo-induced stress, atrophy, apoptosis.

Contacts

Смирнов Алексей Владимирович – д.м.н., доцент, зав. кафедрой патологической анатомии с секционным курсом и курсом патологии Волгоградского государственного медицинского университета, e-mail: alexey-smirnov@rambler.ru