UDK: 616-06:616.379-008.64

FEATURES OF THE DAILY PROFILE OF ARTERIAL PRESSURE AND THE POSSIBILITY OF DOCLINE DIAGNOSTICS OF ARTERIAL HYPERTENSION IN CHILDREN WITH TYPE 1 DIABETES

N.V. Malyuzhinskaya, K.V. Stepanenko, O.V. Polyakova, G.V. Klitochenko, S.A. Emelyanova, O.V. Novikova

ФГБОУ ВО «Волгоградский государственный медицинский университет» Министерства здравоохранения Российской Федерации, кафедра детских болезней педиатрического факультета

Abstract

Diabetic nephropathy takes a leading place among diseases requiring replacement therapy for renal failure, and is also a leading cause of disability and mortality among patients with type 1 diabetes. The development of arterial hypertension is one of the markers of the formation of diabetic nephropathy. We performed a prospective cohort study. A comprehensive clinical and instrumental examination of 78 children with type 1 diabetes was carried out. The features of changes in the daily profile of blood pressure and microcirculatory disorders in children before the formation of diabetic nephropathy were revealed. A mathematical model is developed for predicting the development of arterial hypertension by determining microcirculation parameters using a laser Doppler flowmeter. Early diagnosis will allow timely prescribing of pathogenetic treatment, improving the prognosis of this category of patients.

Keywords

type 1 diabetes, microcirculation disorders, laser Doppler flowmetry, arterial hypertension.

Contacts

Степаненко Ксения Викторовна – ассистент кафедры детских болезней педиатрического факультета, e-mail: kozhevnikova.kv@yandex.ru,