UDK: 616.381-002:615.28-092.9
A.V. Mosolova 1, L.G. Klimova 3, B.S. Sukovatykh 1, M.A. Zatolokina 2, D.A. Semykin 1, E.S. Zatolokina 2
ФГБОУ ВО «Курский государственный медицинский университет» Министерства здравоохранения Российской Федерации, 1кафедра общей хирургии; 2 кафедра гистологии, эмбриологии, цитологии; 3 кафедра микробиологии, вирусологии, иммунологии
Introduction. In emergency surgery, one of the most important problems is to prevent the occurrence of suture failure in the area of surgical intervention. Accordingly, to prevent the development of infection in the area of surgery, it is promising to search for a universal suture material that has a long-lasting antiseptic effect. Materials and methods. The experiment was performed under in vitro and in vivo conditions. The examined samples of suture material were studied on the 1st, 2nd, and 3rd days of the experiment. Results. As a result of in vitro studies, it was found that all the presented samples of suture material that have an antiseptic miramistin on their surface have biocidal activity. According to the in vivo study, the greatest antiseptic effect was shown by filaments coated with miramistin at a concentration of 20 % against all strains of microorganisms. Conclusions. The results of the study indicate the prospects of using a suture material coated with miramistin.
antiseptic suture material, rats, prevention of suture failure, antibacterial activity, antiseptic miramistin, postoperative complications.
Мосолова Анастасия Викторовна – ассистент кафедры общей хирургии, Курский государственный медицинский университет, e-mail: Vodimira@mail.ru