UDK: 615.322:665.527.92

DETERMINATION OF SOME PHENOLIC COMPOUNDS IN THE EXTRACT FROM THE HERB OF INULA BRITANNICA L. BY HPLC

A.F. Ryabukha1, O.K. Abramov1, L.A. Smirnova1, A.V. Yanitskaya2, V.V. Arutyunova2

1 Научный центр инновационных лекарственных средств ФГБОУ ВО «Волгоградский государственный медицинский университет» Минздрава России, Волгоград; 2 ФГБОУ ВО «Волгоградский государственный медицинский университет»

Abstract

Phenolic compounds are an extensive group of biologically active substances, characterized by a wide range оf pharmacological activity. As you know, the chemical composition of plant objects is diverse, but it is in the aboveground part that phenolic compounds predominate. Of particular interest are flavonoids and phenylpropanoids. The identification of compounds of these groups was carried out by HPLC analysis in the grass of inula britannica collected in the Volgograd region. The paper presents chromatograms of water-alcohol extracts with ultraviolet and fluorescent detections, the presence of some hydroxycinnamic acids, namely chlorogenic, caffeic and ferulic acids, as well as luteolin-7-o-glucoside and quercetin from the group of flavonoids.

Keywords

Inula britannica L. (British elecampane), phenolic compounds, chlorogenic acid, caffeic acid, ferullic acid, flavonoids, quercetin, HPLC-analysis.

Contacts

Арутюнова Виктория Валерьевна – старший преподаватель кафедры фармакогнозии и ботаники, Волгоградский государственный медицинский университет, е-mail: gukassova_1990@mail.ru