UDK: 57.01:591.471.35:616.379-008.64-092.9
Vladislav I. Luzin 1 , Alexander V. Torba 2
1, 2 Луганский государственный медицинский университет имени Святителя Луки, Луганск, Луганская Народная Республика
In the study in 140 juvenile rats we tested changes of nanostructure of bone mineral of the hipbone after fracture of the tibia in diabetic juvenile rats. We found out that fracture of the tibia results in instability of crystallites and derangement of crystal lattice of bone mineral. Manifestations peak here was registered on the 30th day of observation. Diabetes produces similar effects, which grow with time. By the 90th day crystallites enlarged by 7,80 % and microtexture decreased 8,34 % (bоth in comparison with the controls). Fracture of the tibia in diabetes results in aggravation of the nanostructure disorders beginning from the 60th day of the experiment. By the 90th day crystallites in this case enlarged by 3,75 % while microtexture coefficient decreased by 5,73 % (in comparison with non-diabetic animals with the tibia fracture).
rats, streptozotocin-induced diabetes, bone injury, bone mineral, nanostructure