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I.V. Ponomareva 1, A.V. Tsukanov 1, M.A. Zatolokina 1, S.V. Ivanov 1, I.S. Ivanov 1, V.A. Lazarenko 1, S.M. Zaitsev 2, E.S. Zatolokina 1
1 Курский государственный медицинский университет, Курск, Россия 2 Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова, Санкт-Петербург, Россия
The paper presents data on studying biocompatibility and tissue response in the implantation zone of collagen-stimulating coated hernio implants. Endoprosthesis of the anterior abdominal wall was carried out in a supraponeurotic manner on rats of the Vistar breed. When using ascorbic acid coated hernioimplant, less pronounced reactive changes were observed in the surrounding tissues, manifested by the absence of a significant number of inflammatory cells, the predominance of fibroblastic elements in the field of view, the activation of which contributed to the early engraftment of the hernioimplant as a result of stimulation of collagenesis. Therefore, it was concluded that the most optimal is hernioimplant coated with ascorbic acid.
hernioimplant, hernioplasty, hernias of the anterior abdominal wall, foreign-body giant cells
Ирина Владимировна Пономарева, ira.ponomareva92@mail.ru