Journal of VolgSMU
Quarterly scientific-practical journal

UDK: 616.34-006.6

A RARE OBSERVATION OF SMALL INTESTINAL TUBULAR ADENOCARCINOMA WITH A NEUROENDOCRINE COMPONENT

S.S. Todorov, S.S. Todorov Jr. , V.Yu. Deribas, A.S. Kazmin, Y.M. Fomchencova

Ростовский государственный медицинский университет, Ростов-на-Дону, Россия

Abstract

Neoplasia of the small intestine are extremely rare. A special place is occupied by tubular adenocarcinomas of the small intestine with a neuroendocrine component, the intravital diagnosis of which is difficult. Materials and methods. The paper presents a clinical observation of a 61-year-old patient who after resection of the small intestine was found to have tubular adenocarcinoma with a neuroendocrine component. Results. Morphoimmunohistochemical examination of the tumor revealed tubular adenocarcinoma with a neuroendocrine component (chromogranin A+, NSE+, alcian+) with invasion into the subserous base. Conclusions. Tubular adenocarcinoma of the small intestine with a neuroendocrine component is a rare neoplasm of the gastrointestinal tract. In vivo pathoanatomical diagnosis of an intestinal tumor should include morphological, histochemical, immunohistochemical studies with the detection of tumor neuroendocrine cells and assessment of malignant potential.

Keywords

small intestine, adenocarcinoma with neuroendocrine component, morphology, histochemistry, immunohisto-chemistry

Contacts

Cергей Сергеевич Тодоров, sertodorov@gmail.com