UDK: 616.6-053.2-076.5-77.1

Importance of cytokine evaluation in obstructive uropathy in children

Khvorostov I.N., Zorkin S.N., Smirnov I.E.

НИИ педиатрии Научный центр здоровья детей РАМН, г. Москва

Abstract

1. Increased TFR-β1 production in blood plasma of patients with obvtructive uropathy is an indicator of fibrogenetic activity. 2. FNO-α production is elevated upon exacerbation of chronic pyelonephritis. 3. Increased FNO-α excretion and decreased IL-10 excretion with urine is an indicator of nephrosclerosis in reflux nephropathy. 4. Irogressing nephrosclerosis with transformation to HPN is accompanied by decreased TFR-β1 concentration in blood plasma. 5. Variations of the inflammatory index in the dynamics of disease underlie the processes of renal parenchyma lesions in children with obstructive uropathy.

Keywords

Contacts

Хворостов Игорь Николаевич – к.м.н., Отделение урологии Научного центра здоровья детей РАМН, nczd@comintern.ru