Journal of VolgSMU
Quarterly scientific-practical journal

UDK: 616.006.6-085.272.4-577.1

The dynamics of changes of morphological and biochemical criteria in due to correction of tumor growtu by antioxydants

S.V., Plotnikova N.A., Kemajkin S.P.

Мордовский государственный университет им. Н. П. Огарева, г. Саранск

Abstract

The analysis of the dynamics of biochemical and morphological changes in a tumor growth in the conditions of the experimental cancerogenesis has confirmed the oncoprotective effect of the antioxidants applied. The positive dynamics of changes in biochemical criteria has been marked when antioxidants werl administerol. The dynamics of the morphological criterion changes has been proved reveal the correlation between the therapeutic effect and the dose of administered antioxidants. The optimal effect is observed when small doses are unf (mexidol 0.1 mg/kg, emoxipin 0.05 mg/kg). Research into antioxidants for the purpose of treating oncological diseases and prevenfor of collateral oncological effects of malignant tumour chemical therapy may be very promising for further investigation.

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Мордовский государственный университет им. Н. П. Огарева, г. Саранск