Journal of VolgSMU
Quarterly scientific-practical journal

UDK: 616.33-001.4-003.93:612.017.1

DYNAMICS OF TISSUE IGG AFTER GASTROPLASTY OF LIVER, SPLEEN AND KIDNEY WOUNDS IN THE EXPERIMENT

O. V. Musatov, S. A. Zurnadjan, J. Kh. Hajrulin

Астраханская государственная медицинская академия

Abstract

Evidence of general immunomorphological regularities of reparative processes in the liver, spleen and kidney wounds after their plasty with a seromuscular flap of the large curvature of the stomach on a vascular pedicle has been carried out on 135 rabbits. The method of direct immunofluorescence by Coons determined the quantity IgG in auto transplants, wounds of organs, layers between them, and also in donor wounds of the stomach, from where the flaps were taken. The follow-up period was from 1 to 360 days. The revealed tissue diffusion and transport IgG in wounds of injured organs most intensively occurred in the first 7 days. The gastric flap, being originally «a tissue drainage», smoothes out the consequences of ischemia around the wounds, accelerates the process of their purification and organization. The increase of IgG from 7-th till 60-th day indicates an«effect of it accumulation» and creation of IgG depot IgG in it.

Keywords

wounds, stomach, liver, spleen, kidney, immunoglobulin, regeneration

Contacts

Мусатов Олег Валентинович — к. м. н., ассистент кафедры оперативной хирургии и топографической анатомии Астраханской государственной медицинской академии, e-mail: agma@astranet.ru