UDK: 616.12. 005.4-053-076.5

Imbalance of proinflammatory cytokines in patients with ischemic heart disease

S. I. Chernova, V. N. Plohov

Отделенческая клиническая больница на станции Волгоград-1 ОАО «РЖД»

Abstract

In ischemic heart disease the level of proinflammatory cytokines IL-1, IL-6 and FNO- is increased. In acute myocardial infarction the highest possible levels of proinflammatory cytokines are noted. In patients with multivascular lesion of coronary arteries the level of cytokines was higher than in patients with a lesion 1—2 main arteries. Patients with high levels of IL-6 and TNF-, even in hemodynamically insignificant stenoses of coronary arteries, should be ranked as a group of high risk of an adverse outcome of ischemic heart disease.

Keywords

proinflammatory cytokines, an acute myocardial infarction, a multivascular lesion of coronary arteries, high risk

Contacts

Чернова Светлана Ивановна — к. м. н., заведующая поликлиникой №1 YEP «Отделенческая клиническая больница», e-mail: sichernova@yandex.ru