Journal of VolgSMU
Quarterly scientific-practical journal

UDK: 616.62-003.7-008 (7)

CALCIUM АNTAGONISTS AND UROLITHIASIS: NEW PERSPECTIVES

A. B. Batko

Санкт-Петербургская государственная медицинская академия им. И. И. Мечникова

Abstract

In view of the exclusive role of ions of calcium in regulation of numerous functions of tissue and cells of the body, great importance is assigned to preparations of calcium antagonists (СА). CA were first applied exclusively in cardiology, but owing to their properties they have found application in obstetrics, gynecology, neurology, immunology, surgery. Despite numerous experimental studies testifying to the expressed cardiovascular properties of CA, indications for their administration constantly expand, which is associated with the physiological role of ions of calcium in providing for vital activity of cells and the whole body. Preliminary results indicate that СА can be administered in new ways — as modulators of apoptosis in renal tissue in urolithiasis and chronic pyelonephritis.

Keywords

calcium, calcium antagonists, urolithyasis

Contacts

Батько Андрей Борисович — к. м. н., заместитель главного врача по лечебной работе Консультативно-диагностической поликлиники, Санкт-Петербург, e-mail: abb69@mail.ru