UDK: 616.5-002.525.2

CHANGES OF LEUKOCYTES LEVEL AND LEUKOCYTE FORMULA IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS DEPENDING ON THE CLINICAL COURSE AND CHARACTER OF THERAPY

G. B. Kuchma, O. V. Bugrova

Оренбургская государственная медицинская академия

Abstract

The level of leukocytes and leukocyte formula both in a disease onset, and upon admission to hospital were studied. It is revealed that the level of leukocytes in patients with systemic lupus erythematosus is closely interconnected with the activity of the disease, exudative nature of internal lesion, extent of haemolysis. However, no interrelations with a total dose of cyclophosphan was established, which testifies to a mostly immune genesis of leukopenia. We should underline the prognostic value of leukocytes decrease in the onset of a disease, which is associated with severe clinical manifestations of systemic lupus erythematosus.

Keywords

systemic lupus erythematosus, leukopenia, neutrophilia, anaemia, thrombocytopenia, lymphadenopathy

Contacts

Кучма Галина Борисовна — к. м. н., доцент кафедры факультетской терапии Оренбургской государственной медицинской академии, e-mail: kuchma1v@yandex.ru