UDK:

Complex therapy diabetic microangiopathy with using of a preparation doxihem

Sobolevskaya N.V., Spasov A.A., Petraevsky A.V., Stepanov A.V., Statzenko M.E.

Кафедра внутренних болезней педиатрического и стоматологического факультетов, кафедра фармакологии, кафедра офтальмологии ВолГМУ

Abstract

The aim of research was to compare efficacy of complex therapy diabetic microangiopathy to using doxihem with standard therapy. 40 patients, 40-65 years, with diabetes mellitus type II with an arterial hypertension and presence of microangiopathy were enrolled in the study. All patients received basic therapy with oral antidiabetes drugs in a combination to an angiotensin converting enzyme (ACE) inhibitor. In experienced group to main therapy was added doxihem on 500 mg 3 times a day. For an evaluation of efficacy of therapy researched rheological parameters of a blood, changes on an eye-ground, function of kidney, signs of peripheral neuropathy. The obtained data testify, that the using doxihem in complex therapy diabetes mellitus type II such as at initial exhibitings microangiopathy allows to slow down development of microvascular complications.

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Contacts

Спасов Александр Алексеевич – ЗДН, член-корр. РАМН, д.м.н., профессор, зав. кафедрой фармакологии ВолГМУ, aaspasov@volgmed.ru, farm@vlpost.ru